Abstract: As one of the main ways to enter the ore body, inclined shaft often threatens the safety of mines and miners due to the exposure of aquifers or toxic and harmful gases during excavation. Aiming at the problem of hydrogen sulfide gas emission when the inclined shaft of Daping Coal Mine passes through Changxing limestone, the geological and hydrogeological conditions of the mine are systematically analyzed. Combined with geophysical exploration and borehole water source identification data, the characteristics of hydrogen sulfide gas emission accompanied by fissure water are clarified. It is determined that the hydrogen sulfide gas comes from the combination of sulfide minerals and structural fracture water in the structural fracture zone, and more hydrogen sulfide gas is produced under the condition of large buried depth and weak runoff. Aiming at the hydrogen sulfide gas in the Changxing limestone of the inclined shaft, the technology of advanced curtain pre-grouting in the wellbore is proposed. The inner and outer two layers of closed curtains are formed by pre-grouting in front of the wellbore, and the ordinary cement-water glass double slurry and the solution type chemical slurry with good injectability are used for segmented high-pressure grouting. Through geophysical exploration, verification hole verification and shaft excavation observation, there is no obvious large amount of hydrogen sulfide gas and fissure water in the whole excavation process, which verifies the effectiveness of the head-on curtain grouting in the inclined shaft, and can provide reference for the treatment of hydrogen sulfide gas in other mines.